The QU-CPH MSc graduate completes his thesis on the economic analysis of health in the treatment of ODA
June 14, 2021 – 9:13
QU-CPH MSc graduate with other officials at an event.
Doha: Graduated from Qatar University College of Pharmacy (QU-CPH), Samaher Alshaibi recently completed and defended her Master of Pharmacy (MSc) thesis titled “Cost-Effectiveness Analysis of Ibuprofen vs. indomethacin or paracetamol for the treatment of patent ductus arteriosus (PDA) in premature infants. ‘
The research was supervised by Dr Daoud Al-Badriyeh, QU-CPH Associate Professor in Pharmacy and Clinical Practice and expert in health economics and outcome research. Professor QU-CPH and Head of Clinical Pharmacy and Practice, Dr Ahmed Awaisu, also co-supervised the research.
The research is the first health economic analysis, nationally and internationally, to assess the cost-effectiveness of all major drug therapy options available for ODA closure in preterm infants in Qatar. It was conducted by the Women Wellness and Research Center, a member of Qatar’s leading healthcare provider, Hamad Medical Corporation (HMC).
The optimal management of PDA, which is an opening between the two main blood vessels leading from the heart that does not close after birth, is very controversial and remains uncertain. There are no universal guidelines or consensus regarding the most appropriate pharmacological treatment and route of administration. Currently, the choice of pharmacological treatment for PDA depends on individual institutions. In HMC in Qatar, the preferred first-line treatment is ibuprofen by intravenous (IV) infusion, which is not based on any local comparative evidence, although IV indomethacin is also available in the HMC drug list for closing the PDA. In Qatar, there is a growing trend to use oral ibuprofen as well as oral paracetamol.
Currently, the simulation-based assessment approach is the future of healthcare and is appropriate. The present study was based on a hypothetical cohort of 5,000 newborns in Qatar. Economic and clinical data were obtained from robust meta-analyzes, local databases, and practice guidelines.
Samaher said, “While it is not easy to complete the masters research in the minimum time required, I have always believed that I can do so with the quality of mentorship I have received. The research topic particularly interested me. But outside of the subject, I learned a lot of skills in research, communication and collaboration. I have published in international journals and presented at international events. I am very satisfied with my MSc experiences and the results generated.
“This analysis is the first economic evaluation in Qatar and the region evaluating ibuprofen versus indomethacin or ibuprofen versus paracetamol for the treatment of ODA in preterm infants, which may be a guide useful for decision-makers in choosing an evidence-based therapy. In addition, since treatments in the neonatal intensive care unit (NICU) are very expensive, incorporating the cost factor when comparing different treatment options can help save hospital resources in the long term ”, a- she added.
Dr Al Badriyeh said: “This research is interesting. Ibuprofen and paracetamol are examples of inexpensive drugs. One might assume that there is no point in performing comparative economic evaluations between these drugs. However, given the different consequences associated with medications, the cost of a baby on these medications can range from 300,000 QR to over 500,000 QR.
Dr Fatima Mraiche, Head of Research and Graduate Studies at QU-CPH, said: “It is always a pleasure to see our students and professors at QU-CPH address issues related to practice using a methodology. rigorous research. It is a clear indication of the essential bridge between academia and practice, a bridge that leads to gradual changes in the health and well-being of society.